Journal of Dentistry of Tehran University of Medical Sciences 2018. 15(2):116-122.

Evaluation of Microhardness of Mineral Trioxide Aggregate after Immediate Placement of Different Coronal Restorations: An In Vitro Study
Maryam Kazemipoor, Niloofar Azizi, Farnaz Farahat


Objectives: The purpose of this research was to evaluate the effect of immediate placement of different restorative materials in comparison with a temporary restoration on the surface microhardness of mineral trioxide aggregate (MTA).

Materials and Methods: Access cavities were prepared in 40 extracted human molars, and a 3-mm layer of MTA was placed in the pulp chamber. The samples were divided into eight groups (n=5). Ten minutes after the MTA placement, two groups were restored with Zonalin temporary restoration, while the other six groups were restored with glass-ionomer cement (GIC), resin-modified glass-ionomer (RMGI), or resin-based composite. In each group, the Vickers microhardness (VMH) of MTA was determined after 7 and 21 days. Data were entered into SPSS 17 software program and were analyzed by two-way analysis of variance (ANOVA). The significance level was set at 5%.

Results: The type of restorative materials had a statistically significant effect on the microhardness of MTA (P=0.002). However, the microhardness of MTA was neither significantly influenced by the timing of final restoration (P=0.246) nor by the time-material interaction (P=0.116).

Conclusions: Based on the results of the present study and by considering the limitations of laboratory studies, it is recommended to postpone the placement of final restorations until the underlying MTA is completely set. Otherwise, in the clinical conditions in which early covering of MTA is recommended, sufficient moist-curing and hydration should be guaranteed by selecting a restorative material with the lowest hydrophilic interaction energy.


Dental Restoration; Mineral Trioxide Aggregate; Composite Resins; Glass Ionomer Cements

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- Tsujimoto M, Tsujimoto Y, Ookubo A, Shiraishi T, Watanabe I, Yamada S, et al. Timing for composite resin placement on mineral trioxide aggregate. J Endod. 2013 Sep;39(9):1167-70.

- Eid AA, Komabayashi T, Watanabe E, Shiraishi T, Watanabe I. Characterization of the mineral trioxide aggregate–resin modified glass ionomer cement interface in different setting conditions. J Endod. 2012 Aug;38(8):1126-9.

- Koh ET, McDonald F, Pitt Ford TR, Torabinejad M. Cellular response to mineral trioxide aggregate. J Endod. 1998 Aug;24(8):543-7.

- Lee YL, Lee BS, Lin FH, Yun Lin A, Lan WH, Lin CP. Effects of physiological environments on the hydration behavior of mineral trioxide aggregate. Biomaterials. 2004 Feb;25(5):787-93.

- Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review--Part I: chemical, physical, and antibacterial properties. J Endod. 2010 Jan;36(1):16-27.

- Torabinejad M, Hong CU, McDonald F, Pitt Ford TR. Physical and chemical properties of a new root-end filling material. J Endod. 1995 Jul;21(7):349-53.

- Nandini S, Ballal S, Kandaswamy D. Influence of glass-ionomer cement on the interface and setting reaction of mineral trioxide aggregate when used as a furcal repair material using laser Raman spectroscopic analysis. J Endod. 2007 Feb;33(2):167-72.

- Yesilyurt C, Yildirim T, Taşdemir T, Kusgoz A. Shear bond strength of conventional glass ionomer cements bound to mineral trioxide aggregate. J Endod. 2009 Oct;35(10):1381-3.

- Tunç EŞ, Sönmez IS, Bayrak S, Eğilmez T. The evaluation of bond strength of a composite and a compomer to white mineral trioxide aggregate with two different bonding systems. J Endod. 2008 May;34(5):603-5.

- Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review--Part III: Clinical applications, drawbacks, and mechanism of action. J Endod. 2010 Mar;36(3):400-13.

- Fernández-Yáñez Sánchez A, Leco-Berrocal MI, Martínez-González JM. Metaanalysis of filler materials in periapical surgery. Med Oral Patol Oral Cir Bucal. 2008 Mar 1;13(3):E180-5.

- Torabinejad M, Parirokh M. Mineral trioxide aggregate: a comprehensive literature review--part II: leakage and biocompatibility investigations. J Endod. 2010 Feb;36(2):190-202.

- Kuratate M, Yoshiba K, Shigetani Y, Yoshiba N, Ohshima H, Okiji T. Immunohistochemical analysis of nestin, osteopontin, and proliferating cells in the reparative process of exposed dental pulp capped with mineral trioxide aggregate. J Endod. 2008 Aug;34(8):970-4.

- Bozeman TB, Lemon RR, Eleazer PD. Elemental analysis of crystal precipitate from gray and white MTA. J Endod. 2006 May;32(5):425-8.

- Reyes-Carmona JF, Felippe MS, Felippe WT. Biomineralization ability and interaction of mineral trioxide aggregate and white portland cement with dentin in a phosphate-containing fluid. J Endod. 2009 May;35(5):731-6.

- Mente J, Geletneky B, Ohle M, Koch MJ, Friedrich Ding PG, Wolff D, et al. Mineral trioxide aggregate or calcium hydroxide direct pulp capping: an analysis of the clinical treatment outcome. J Endod. 2010 May;36(5):806-13.

- Chng HK, Islam I, Yap AU, Tong YW, Koh ET. Properties of a new root-end filling material. J Endod. 2005 Sep;31(9):665-8.

- Patil A, Aggarwal S, Kumar T, Bhargava K, Rai V. The evaluation of interfaces between MTA and two types of GIC (conventional and resin modified) under an SEM: An in vitro study. J Conserv Dent. 2016 May-Jun;19(3):254-8

- Nekoofar MH, Adusei G, Sheykhrezae MS, Hayes SJ, Bryant ST, Dummer PM. The effect of condensation pressure on selected physical properties of mineral trioxide aggregate. Int Endod J. 2007 Jun;40(6):453-61.

- Kayahan MB, Nekoofar MH, Kazandağ M, Canpolat C, Malkondu O, Kaptan F, et al. Effect of

acid‐etching procedure on selected physical properties of mineral trioxide aggregate. Int Endod J. 2009 Nov;42(11):1004-14.

- Lee YL, Lin FH, Wang WH, Ritchie HH, Lan WH, Lin CP. Effects of EDTA on the hydration mechanism of mineral trioxide aggregate. J Dent Res. 2007 Jun;86(6):534-8.

- Walker MP, Diliberto A, Lee C. Effect of setting conditions on mineral trioxide aggregate flexural strength. J Endod. 2006 Apr;32(4):334-6.

- Gancedo-Caravia L, Garcia-Barbero E. Influence of humidity and setting time on the push-out strength of mineral trioxide aggregate obturations. J Endod. 2006 Sep;32(9):894-6.

- Ballal S, Venkateshbabu N, Nandini S, Kandaswamy D. An in vitro study to assess the setting and surface crazing of conventional glass ionomer cement when layered over partially set mineral trioxide aggregate. J Endod. 2008 Apr;34(4):478-80.

- Loxley EC, Liewehr FR, Buxton TB, McPherson JC 3rd. The effect of various intracanal oxidizing agents on the push-out strength of various perforation repair materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003 Apr;95(4):490-4.

- Khoroushi M, Keshani F. A review of glass-ionomers: From conventional glass-ionomer to bioactive glass-ionomer. Dent Res J (Isfahan). 2013 Jul;10(4):411-20.


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