Evaluation of the Effect of Neem and Mango Extract on S. Mutans In Vitro and Assessment of its Antiplaque, Antigingivitis Efficacy, and Effect on Salivary Ph and Taste Acceptability in Children
Introduction: Chlorhexidine has earned its eponym as gold standard; however, its limitations have paved the way for herbal mouthrinses.
Aim: To assess in vitro the Minimal Inhibitory Concentration (MIC) of neem and mango extracts on S. Mutans, preparation of mouthrinse using the extracts and in vivo assessment of the prepared mouthrinse on plaque, gingivitis, salivary pH and taste acceptability in comparison to chlorhexidine in children.
Methods: The Minimal Inhibitory Concentration (MIC) for neem and mango extracts on S. mutans were evaluated. The effective MIC was used to prepare the mouthrinse which was given to 90 children for a period of 21 days. The plaque index, gingival index and salivary pH were assessed at baseline, day 7 and day 21. The taste acceptability was also assessed.
Results: The MIC achieved was at 25% concentrations with both the extracts. There was a statistically significant reduction in plaque scores, gingival scores and salivary pH in all the three study groups after 21 days. (P<0.001)
Conclusion: Neem and Mango mouthrinses could be used as an effective alternative to chlorhexidine in children.
Keyword: Chlorhexidine, Herbal extracts, Oral hygiene. Salivary pH
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