A Case Report of a Gingival Plasma Cell Granuloma in a Patient on Antihypertensive Therapy: Diagnostic Enigma

  • Ruchi Gulati Department of Periodontology, Government College of Dentistry, Madhya Pradesh, India
  • Madhu Singh Ratre Department of Periodontology, Government College of Dentistry, Madhya Pradesh, India
  • Shaleen Khetarpal Department of Periodontology, Government College of Dentistry, Madhya Pradesh, India
  • Manish Varma Department of Periodontology, Government College of Dentistry, Madhya Pradesh, India
Keywords: Amlodipine, Diagnosis, Gingival Overgrowth, Plasma Cells, Plasma Cell Granuloma

Abstract

The aim of the present report was to discuss a unique case of gingival plasma cell granuloma (PCG) in a hypertensive patient on Amlodipine therapy. Also, we attempt to emphasize the importance of considering primary and advance investigations before making a definite diagnosis. PCG is an extremely rare, reactive, non-neoplastic lesion characterized by the predominance of polyclonal plasma cells. Drug-induced gingival overgrowth is a known side effect of Amlodipine. A hypertensive 60-year-old female patient reported with a chief complaint of swollen gums and discomfort in the upper front teeth region. A provisional diagnosis of Amlodipine-induced gingival overgrowth, combined gingival overgrowth, and fibroma was suggested. Surprisingly, histopathology revealed it to be a plasma cell lesion which was confirmed by advanced investigations, thereby establishing a confirmatory diagnosis of PCG.

Author Biographies

Ruchi Gulati, Department of Periodontology, Government College of Dentistry, Madhya Pradesh, India

Department of Periodontology,

Post-graduate student.

Madhu Singh Ratre, Department of Periodontology, Government College of Dentistry, Madhya Pradesh, India

Reader, Department of Periodontology,
Government College of Dentistry,
Indore (M.P.)

Shaleen Khetarpal, Department of Periodontology, Government College of Dentistry, Madhya Pradesh, India

Lecturer, Department of Periodontology, Govt. College of Dentistry, Indore

Manish Varma, Department of Periodontology, Government College of Dentistry, Madhya Pradesh, India

Tutor, Department of Periodontology, Govt. College of Dentistry, Indore

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Published
2019-04-30
How to Cite
1.
Gulati R, Ratre M, Khetarpal S, Varma M. A Case Report of a Gingival Plasma Cell Granuloma in a Patient on Antihypertensive Therapy: Diagnostic Enigma. Front Dent. 16(2):144-148.
Section
Case Report