Regenerative Treatment of Peri-Implantitis: A Systematic Review
Aim: the aim of this Systematic Review (SR) was to assess the clinical efficacy of bone regeneration on the treatment of peri-implantitis.
Material and methods: Electronic searches were performed to identify randomized clinical trials (RCTs) and cases series (CS) on treatment of peri-implantitis using bone regeneration procedures with at least 6 months of follow-up. Applying guidelines of the Preferred Reporting Items for Systematic Review and Meta Analyses statement (PRISMA). The risk of bias was assessed using the Cochrane Collaboration’s Risk of Bias tool.
Results: 2 RCTs and 16 cases series with a total of 520 treated patients (2002implants) were included. This systematic review showed that: Bone regeneration procedures still a controversial subject in terms of bone fill ; only 2 studies reported a gain of bone level statistically significant and 4 studies reported a gain of bone level no statistically significant. However, in the other studies the gain of bone level was obtained but the p-value was not indicated. Pocket depth reduction varying from study to study and even from case to case; 4 studies reported a reduction of pocket depth statistically significant and 4 others studies reported a reduction of pocket depth no statistically significant. However, in the other studies the reduction of pocket depth was reported without mentioning if it was statistically significant. No improvement in Recession
Conclusion: Evaluation of the effectiveness of bone regeneration techniques in this systematic review presented limitations related to heterogeneity in patient selection the means of disinfection and decontamination ....
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